Sigma-Aldrich Fetal Bovine Serum (FBS)
Premium Australia-origin FBS for reliable and consistent cell culture performance.
Sigma-Aldrich Fetal Bovine Serum (FBS) is a high-quality serum supplement designed to support robust growth and maintenance of mammalian and hybridoma cell cultures. Sourced from Australia and manufactured under strict quality controls, Sigma FBS provides excellent consistency between lots, helping you achieve reproducible experimental outcomes. Australia carries the best possible rating in relation to Geographical Bovine Spongiform Encephalopathy (BSE) Risk (GBR) as designated by the Scientific Steering Committee on the Geographical Risk of Bovine Spongiform Encephalopathy. The classification for Australia is GBR Level I.
Each lot undergoes extensive testing for endotoxin levels, haemoglobin content, bacteria, viruses, and mycoplasma contamination. Triple filtration through 0.1 µm membranes under aseptic conditions ensures high sterility and dependable performance in sensitive cell culture applications.
- Australia origin: sourced from a region with negligible BSE risk (GBR Level I)
- Extensively tested: screened for endotoxin, haemoglobin, bacteria, viruses, and mycoplasma
- Triple 0.1 µm sterile filtration: improves sterility and consistency
- Excellent lot-to-lot consistency: helps improve reproducibility between experiments
- Suitable for mammalian and hybridoma cell culture
- USDA approved: trusted quality for research applications
- Reliable supply chain: globally recognised Sigma-Aldrich quality standards
Technical Specifications
| Biological Source | Bovine fetus |
| Quality Segment | 500 |
| Sterility | Sterile-filtered |
| Product Line | FBS Classic |
| Quality | USDA approved |
| Composition | Bovine IgG ≤1 mg/mL; Haemoglobin ≤20 mg/dL |
| Origin | Australia origin |
| Applications | Suitable for mammalian cell culture and hybridoma applications |
| Endotoxin Level | ≤10 EU/mL endotoxin |
| Shipping Conditions | Shipped on dry ice |
| Storage Temperature | −20°C |
Available Pack Sizes
| Product Code | Pack Size | Description |
|---|---|---|
| F9423-50ML | 50 mL | Australia-origin fetal bovine serum, sterile-filtered |
| F9423-100ML | 100 mL | Australia-origin fetal bovine serum, sterile-filtered |
| F9423-500ML | 500 mL | Australia-origin fetal bovine serum, sterile-filtered |
| F9423-1000ML | 1000 mL | Australia-origin fetal bovine serum, sterile-filtered |
FBS quality can significantly impact cell growth, viability, transfection efficiency, and assay reproducibility. Researchers commonly look for low endotoxin levels, consistent growth performance, and dependable sourcing when selecting serum. Sigma-Aldrich FBS addresses these concerns through rigorous quality testing and validated manufacturing processes, helping minimise variability in sensitive cell culture workflows.
Australia-origin serum is particularly valued due to its strong biosecurity standards and low BSE risk classification. Combined with Sigma-Aldrich’s established reputation in life science research, this makes Sigma FBS a trusted option for academic, biotechnology, pharmaceutical, and diagnostic laboratories.





